Clinical factors associated with hypomagnesemia among patients with cardiac conditions: cross-sectional study

  • Arlyn Gaballo Awing Davao Regional Medical Center
  • Aryeel Llanos Davao Regional Medical Center


Background. Serum magnesium levels are usually measured and corrected, if warranted, among patients with cardiac diseases.

Objective. To determine the rate of and clinical factors associated with hypomagnesemia among patients with cardiac conditions.

Design. Cross-sectional study.

Setting. Davao Regional Medical Center (DRMC) in Tagum City, Philippines, from January 2014 to January 2016.

Participants. 59 males and 53 females with cardiac diagnoses and serum magnesium level determination results.

Main outcome measures. Rate of hypomagnesemia, odds ratios (95% CI) of having hypomagnesemia for selected clinical factors.

Main results. The mean age of the patients was 60.72 ± 16.73 years. The mean serum magnesium level was 0.75 ± 0.23 mmol/L, and 47/112 (41.96%) had hypomagnesemia (serum magnesium <0.7 mmol/L). Unadjusted prevalence odds ratios (POR) for having hypomagnesemia were significantly high for chronic obstructive pulmonary disease (COPD) comorbidity (POR=5.50; 95% CI 1.09 to 27.76; p=0.0392), stroke comorbidity (POR=2.78; 95% CI 1.15 to 6.71; p=0.0227), taking diuretic medications (POR=4.66; 95% CI 1.38 to 15.71; p=0.0132), and having atrial fibrillation during the admission (POR=2.26; 95% CI 1.04 to 4.91; p=0.0394).

Conclusion. In this study, 41.96% of the patients had hypomagnesemia. COPD and stroke comorbidities, diuretic therapy, and atrial fibrillation among patients with cardiac conditions were all significantly associated with hypomagnesemia.

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Jun 25, 2018